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Classic microbiology meets modern technology.
The Soleris™ system is a rapid optical system for the detection of microbial contamination based on an innovative application of classic microbiology familiar to microbiologist. The optical assay measures microbial growth by monitoring pH and other biochemical reactions that generate a color change as microorganisms in the broth grow and metabolize. The results are displayed by color-coded monitoring with an alert on samples out of specification.
Sensitivity of the technology ranges from a single organism per vial to 108 CFU/mL (upper limit).
The technology has enjoyed success by customers throughout the world, over 600 instruments used by over 350 companies in over 30 countries.
The technology is based on monitoring changes in the chemical characteristics of microbial liquid growth medium in which the target microorganisms grow and are detected by optically sensitive reagents. The reagents change their spectral patterns as the metabolic process takes place. These changes are detected photometrically by an optical instrument and monitored at predetermined time intervals.
The key to the technology is the monitoring of these changes in a semifluid zone of the patented organism-specific vial (see Soleris vial). This zone is separated from the liquid medium, thereby eliminating the masking of the optical pathway by the product, or microbial turbidity. Changes in color, expressed as optical units, are sensed by the optical sensor and recorded in the computer. Sample volume of up to 5 mL can be used. Various dyes, which are indicators of metabolic activity such as pH, redox, and enzymatic activity, can be utilized in the system. |
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